PGX

What is Pharmacogenetics?

Pharmacogenetics is the study of how genes affect a person’s response to drugs. This relatively new field combines pharmacology (the science of drugs) and genomics (the study of genes and their functions) to develop effective, safe medications and doses that will be tailored to a person’s genetic makeup.

Many drugs that are currently available are “one size fits all,” but they don’t work the same way for everyone. It can be difficult to predict who will benefit from a medication, who will not respond at all, and who will experience negative side effects (called adverse drug reactions).

Adverse drug reactions (ADRs) are a significant cause of hospitalizations and deaths in the United States and are a are a long-standing and largely neglected major medical problem. ADRs, often called side effects, are not medical errors as they occur within the FDA-approved dosage and labeling recommendations. The recently reported genetically-based problems with Plavix and codeine reported by the FDA are a prime example of specific drugs creating ADRs.

Researchers are learning how inherited differences in genes affect the body’s response to medications. These genetic differences are used to predict whether a medication will be effective for a particular person and to help prevent adverse drug reactions.

Financial Consequences of Adverse Drug Reactions

770,000

Over 770,000 people are injured or die each year in hospitals from ADRs.

$5,600,000

ADRs may cost up to $5.6 million each year per hospital depending on hospital size.

$5,600,000,000

National hospital expenses to treat patients who suffer ADRs during hospitalization range between $1.56 and $5.6 billion annually.

Additional Financial Consequences:

  • $289 billion in added health care costs per year.

  • Medication Adherence for Chronic Disease.

  • HMOs spend more treating ADRs than on drugs.

  • ADRs are the cost leader for malpractice payouts.

  • Up to one-third of drug prescriptions are not needed and therefore wasted.

Assurance of Patient Compliance is Actively Promoted Through Insurers and Government Payers

  • Adverse Drug Reactions (ADRs) are reduced by the practitioner being made aware of all medications the patient is taking both prescribed and non-prescribed ADRs cannot be predicted by patient characteristics or drug type.

  • Costs of ADRs include emergency department visits, hospitalizations and litigation.

  • Average costs for ADRs are up to $5,000 for outpatient and greater than $15,000 for inpatient occurrence.

To download PDF versions of available genetic tests, click below.

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Standard Medical Equipment Systems, LLC – DBA, (“Standard Med” ) is a certified minority (MBE) Veteran (SDVOSB) owned company, certified by the Center for Veteran Enterprises, (CVE).— Standard Med was established by Anthony B. Goodesmith, in the year 2005, to deliver high quality medical devices and laboratory equipment. Mr. Goodesmith served as a highly decorated combat signaler/communications officer in the U.S. Army and New Jersey National Guard for over 18 years. His units took part in Operation Desert Storm, and several other military campaigns after the 9/11 U.S. Terror Attacks (Operations Enduring Freedom and Noble Eagle). He received his B.S. in Marketing and Media Arts from Long Island University, NY, and his Master’s degree in Biotechnology Management from The University of Maryland University College (UMUC).Mr. Goodesmith has been working in the health care, medical industry in sales and management for over 20 years at several Fortune 500 pharmaceutical and medical device companies. Such as Eli Lilly & Company, Solvay Pharmaceuticals, AstraZeneca, Inc., Roche Laboratories, Inc. and now Standard Medical Systems, LLC. He has received the Elite Salesman Award, President’s Award, U.S. Congressional VIP Citation, and achieved #1 status in selling various pharmaceutical drugs and medical devices throughout his career. Mr. Goodesmith shares his tremendous expertise as a staff writer for the DC Health-Technology Examiner, based on his exceptional knowledge about the epidemiology of health-related issues and via medical device, regenerative, biological solutions. You may reach Mr. Goodesmith at his corporate email address: tony@standardmed.us. We pride ourselves on our distinct array of medical devices and diagnostic equipment we offer to the healthcare community, which delivers the highest quality control, safety and efficacy with the latest breakthroughs in medical technology.

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